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New Markers Predict Progression in Oral Cancer

Posted on Wednesday, October 9, 2013

August 21, 2012 — Medscape Today reports that researchers have made a possible breakthrough that could help curtail the rising incidence of oral cancer, according to a prospective cohort study in Cancer Prevention Research. A group of molecular markers has been identified that can differentiate which oral premalignant lesions have a high risk for progression to cancer.


"The results of our study should help to build awareness that not everyone with a low-grade oral premalignant lesion will progress to cancer," said Miriam Rosin, PhD, director of the Oral Cancer Prevention Program at the BC Cancer Agency in Vancouver, British Columbia, Canada. "They should also begin to give clinicians a better idea of which patients need closer follow-up."


The prospective cohort study, published online August 21 in Cancer Prevention Research, is the largest longitudinal study of low-grade oral premalignant lesions from a population-based patient group. It confirms previously reported data and provides the first validated molecular model to differentiate low-grade oral dysplasia at low risk for progression from lesions at greater risk, the researchers note.


To read the entire Medscape Today article, click here.

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