A recent prospective study was conducted to evaluate the benefit of direct visual fluorescent examination (DVFE) using the VELscope ® device (Visually Enhanced Lesion Scope; LED Dental; www.velscope.com) in routine screening for potentially malignant oral mucosal lesions in a general population of patients presenting for dental care, according to Medscape Today. A total of 130 patients were recruited for this study and completed the clinical protocol.
Results of the study (“The Role of Direct Visual Fluorescent Examination [VELscope] in Routine Screening for Potentially Malignant Oral Mucosal Lesions.” McNamara KK, Martin BD, Evans EW, Kalmar JR. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;114:636-643) demonstrated that DVFE failed to identify a single mucosal abnormality that had already been detected by conventional oral examination. Furthermore, 42 of the 130 patients (32.3%) had 1 or more areas of visual fluorescence loss, yet microscopic evidence of precancer or oral cancer was identified in only 1 individual. On the basis of these results, McNamara and colleagues concluded that use of DVFE does not provide diagnostic benefit beyond conventional oral examination alone in routine screening for potentially malignant oral mucosal lesions.
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